2025 NFC, AFC Championship Game betting guide, odds, props: AI, model, expert, parlay, and DFS picks revealed



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Kansas City’s quest to 3-peat continues on Sunday when Patrick Mahomes and the Chiefs host Josh Allen and the Bills in the 2025 AFC Championship Game. These two teams squared off in Buffalo on Nov. 17, a game that resulted in a 30-21 win for the Bills. However, Allen has yet to beat Mahomes and the Chiefs in the NFL playoffs. According to the latest 2025 AFC Championship odds, Kansas City is a 1.5-point favorite at home, with an over/under of 47.5. The Chiefs are 3-9 against the spread in their last 12 games, but should you back Andy Reid’s squad with your 2025 AFC Championship picks? 

The 2025 NFC Championship Game will feature two bitter NFC East rivals. The Philadelphia Eagles will host the Washington Commanders on Sunday at 3 p.m. ET. Philadelphia is 6-2 in its last eight home games against Washington and is favored by six points with an over-under of 47.5. If you are looking for NFL picks, NFL parlays, or NFL DFS picks for the NFL championship round, SportsLine has you covered with its proven model, AI PickBot, and team of expertsThey even have one pick that returns well over +10000, so be sure to see what they have to say.

Self-learning AI reveals top NFL picks

SportsLine AI has hit a whopping 1,390 4.5- and 5-star NFL prop picks since the start of last season at 48% accuracy. Now, it is back with its picks on the spread, money line and total for the AFC and NFC Championship Games. It is backing the Chiefs to cover as 1.5-point favorites against the Bills on Sunday in a game with an over/under of 47.5. See AI picks for both conference championship games right here. 

NFL parlay picks could generate massive payouts

SportsLine’s model has returned well over $7,000 on top-rated picks since its inception, so those picks can confidently be used to fill out NFL parlay picks on betting apps. The model has built a five-team parlay for Sunday that pays 25-1, and one of the legs is Over 47.5 points in Commanders vs. Eagles. The Over hits in well over 50% of simulations, and the rest of the five-team parlay can be found here. 

NFL DFS picks from top experts 

SportsLine has a DFS optimizer that simulates every game 10,000 times and uses info from the SportsLine Projection Model and DFS Professional Millionaire Mike McClure to identify top DFS picks/plays for any slate on sites like FanDuel and DraftKings. It has Eagles quarterback Jalen Hurts as its top quarterback, while Eagles running back Saquon Barkley is its top running back. Here are the Optimizer’s complete NFL DFS rankings. 

Advanced NFL model simulates AFC, NFC Championship Games 10,000 times 

SportsLine’s model enters the championship round of the 2025 NFL playoffs on a 31-15 betting hot streak on top-rated NFL picks this year — a stunning 67% success rate. Longer term, it is on a 211-143 roll on top-rated NFL picks that dates back to the 2017 season and a 65-36 roll on top-rated NFL picks since Week 7 of 2022. The model has revealed picks for the AFC and NFC Championship Games, and one of its favorite picks is the Over (47.5) in Commanders vs. Eagles. You can find the model’s picks for both games here.

NFL Vegas expert picks revealed 

SportsLine has an expansive team of NFL experts who provide quality betting advice for every game on the schedule. Insider Jason La Canfora has analyzed the NFL odds board and locked in his best bets for Commanders vs. Eagles and Bills vs. Chiefs, including Kansas City (-128) to win outright at home. La Canfora’s NFL best bets can be found here. 

Eric Cohen, who finished the regular season with a 180-92 (66%) record, has exact score predictions for both the AFC and NFC Championship Games. He likes the Over in Bills vs. Chiefs and expects both games to be decided by the thinnest of margins. Hit any of his exact score picks and you’re looking at a payout well over 100-1. That pick, along with his prediction for both games, is available here. SportsLine’s advanced computer model has also locked in its exact score predictions for the AFC and NFC Championship Games right here.  

Commanders vs. Eagles picks (Sunday, 3 p.m. ET)

Bitter NFC East rivals collide when the Philadelphia Eagles host the Washington Commanders in the 2025 NFC Championship Game. Washington is 5-1 in its last six games on the road, while Philadelphia is 9-0 in its past nine games at home. SportsLine’s model likes the Over (47.5) in that game and has also revealed its picks on the spread and money line. NFL expert Larry Hartstein, who is 25-13 over his last 38 against the spread picks involving Philadelphia, has locked in his best bet for this NFC showdown right here.

SportsLine AI has hit a whopping 1,390 4.5- and 5-star NFL prop picks since the start of last season at 48% accuracy. Now, it has locked in its top player props involving players like Jalen Hurts, Jayden Daniels, Saquon Barkley and Terry McLaurin. One of its top NFL prop picks is Daniels going over 1.5 passing touchdowns. The AI PickBot projects Daniels will finish with 2.0 passing touchdowns, rating the over as a 4.5-star play. See the AI PickBot’s top player props for Commanders vs. Eagles right here. 

Bills vs. Chiefs picks (Sunday, 6:30 p.m. ET)

Familiar foes face off when the Kansas City Chiefs host the Buffalo Bills in the 2025 AFC Championship Game. Buffalo is 4-2 in its last six games against Kansas City, but the Chiefs have won 12 consecutive games at home. SportsLine’s model likes the Over (47.5) in that game and has also revealed its picks on the spread and money line. NFL expert Mike Tierney, who is on a 47-30-4 roll on picks involving the Bills, has locked in a best bet for this AFC showdown right here. 

SportsLine AI has hit a whopping 1,390 4.5- and 5-star NFL prop picks since the start of last season at 48% accuracy. Now, it has locked in its top player props involving players like Patrick Mahomes, Josh Allen, Travis Kelce and James Cook. One of its top NFL prop picks is Allen going over 229.5 passing yards. The AI PickBot projects Allen will finish with 255.4 passing yards, rating the over as a 4.5-star play. See the AI PickBot’s top player props for Chiefs vs. Bills right here. 

How to bet on NFL games this week

Here are some of the sportsbooks to bet on NFL games this week, along with the various NFL sportsbook promos they currently offer.





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